The key target AKT1, also known as protein kinase B, belongs to the family of serine/threonine kinases that regulate processes such as metabolism, proliferation, growth, and angiogenesis.[24] Studies have shown that inhibiting the activity of AKT1 can effectively improve the pain symptoms of endometriosis and the inflammatory response to relieve the pain symptoms of PD. This evidence concerns the gene AKT1 and endometriosis.