MYC and central nervous system cancer: In liver cancer, MYC can influence metastasis in both EMT-dependent and -independent ways.[16,17] In glioma cells, C-MYC also enhances its stimulatory effects on EMT by inducing the Wnt/β-catenin pathway.[18] In this case, the tumor’s invasion of the choroid plexus caused the tumor cells to disseminate through the CSF to ECM.