LEP and obesity due to melanocortin 4 receptor deficiency: The novelty of the research relies on its ability to efficiently examine the interconnection of renal function, lipid metabolism, glycated hemoglobin (HbA1c), and serum leptin basically amongst the study population and provide a guide on possible therapies and interventions for people with obesity and T2DM so that metabolic control can be improved and associated complications can be better managed or prevented.