The study was also able to observe a significant correlation between serum leptin and HbA1c, making it responsible for impaired glycemic control as indicated by the rise in HbA1c values in individuals with type 2 diabetes and obesity, thus suggesting the potential role of serum leptin in impacting glucose metabolism and the onset and advancement of type 2 diabetes. The gene discussed is LEP; the disease is obesity due to melanocortin 4 receptor deficiency.