The term “lipid metabolism” describes how the body breaks down and uses fats.[10] Lipid metabolism is frequently dysregulated in people with T2DM and obesity, resulting in increased levels of blood lipids such as cholesterol and triglycerides.[11] To explore the potential association between leptin levels and lipid metabolism in this population, the study examines the relationship between circulating leptin concentrations and lipid profile parameters among diabetic and nondiabetic individuals. Here, LEP is linked to obesity due to melanocortin 4 receptor deficiency.