Further analysis revealed that KAI1 expression was positive in 26 of 48 cases (54.2%) in the group with tumor sizes <4.0 cm, while only 16 of 58 cases (27.6%) with tumors measuring 4.0 cm or greater showed KAI1 positivity, a difference that was statistically significant (χ2 = 7.757, P = .005). This evidence concerns the gene CD82 and neoplasm.