In the primary FL tumor, we identified oncogenes with higher chromatin accessibility, including JUN, DICER1, CIITA, SAMD2, MSH6, RUNX1, PIK3R1, and MYD88. In contrast, the relapsed DLBCL tumor exhibited higher chromatin accessibility in genes such as CASP9, STAT3, REL, BCL2, NPM1, and LYN (Fig. 5j). The gene discussed is MSH6; the disease is diffuse large B-cell lymphoma.