TNF and breast cancer: Meanwhile, previous studies have shown that TNF‐α induces up‐regulation of TRIM15 expression in breast cancer cells through activation of the NF‐κB pathway.[12] Similarly, the KEGG enrichment analyses of the RNA‐seq data of the HFD and the ND groups’ xenografts showed that the NF‐κB pathway was significantly dysregulated (Figure 1G).