The results from Genomics of Drug Sensitivity in Cancer (GDSC) showed that HTR7 expression was negatively correlated with IC50 of a larger number of drugs, including 5-fluorouracil, gemcitabine, sunitinib, tipifarnib, and trametinib, implying that these drugs may be sensitive to high HTR7 expression (Fig 12A). The gene discussed is HTR7; the disease is cancer.