In this study, we examine the impact of PPARγ, a nuclear receptor that plays a central role in adipocyte differentiation, lipid uptake, and anti‐inflammatory signaling, making it a compelling candidate for mediating the intersection between systemic metabolism and breast cancer outcomes (Chi et al., 2021; Hernandez‐Quiles et al., 2021; Li et al., 2024). Here, PPARG is linked to breast cancer.