INS and major depressive disorder: For insulin, based on the model adjusted for age, sex, area‐level deprivation, smoking status, year of type 2 diabetes diagnosis and baseline HbA1c and eGFR, the rate of initiation was 22% higher (HR 1.22, 95% CI: 1.04–1.44) in people with bipolar disorder, 43% higher in people with major depression (HR 1.43, 95% CI: 1.35–1.52) but 22% lower (HR 0.78, 95% CI: 0.69–0.89) in people with schizophrenia (Table S7).