SHBG and polycystic ovary syndrome: Curcumin significantly improved BMI, fasting blood glucose, fasting insulin, HDL-C, HOMA-IR, insulin, QUICK, SHBG, TC, total cholesterol, total testosterone, waist circumference, and WHR in PCOS patients, but had no significant effect on gastrointestinal adverse events, postprandial blood glucose, or pregnancy rates.