The search term for PubMed was compiled as follows: (("Type 2 diabetes mellitus"[tiab] OR "Type 2 diabetes"[tiab] OR T2DM[tiab] OR "Non-insulin dependent diabetes"[tiab]) AND ("Empagliflozin"[tiab] OR "Jardiance"[tiab] OR "SGLT2 inhibitor"[tiab] OR "Sodium-glucose cotransporter 2 inhibitor"[tiab] OR "Sodium glucose transporter 2 inhibitor"[tiab] OR "Gliflozin"[tiab] OR "Gliflozins"[tiab]) AND ("Heart failure hospitalization"[tiab] OR "HF hospitalization"[tiab] OR "Heart failure events"[tiab] OR "HF events"[tiab] OR "Heart failure exacerbation"[tiab] OR "Decompensated heart failure"[tiab])). This evidence concerns the gene SLC5A2 and diabetes mellitus.