ITGB5 and neoplasm: In the GSE154778 dataset, analysis demonstrated that COL7A1 and ITGB5 were predominantly expressed in tumor-associated fibroblasts, ITGA6 was detectable in both tumor epithelial and endothelial cells, NTN4 was primarily localized within tumor epithelial cells, whereas ITGA7 and ITGB7 exhibited relatively low expression levels overall (Figure 15).