Spatial maps showed that their TAM to MES2-like interactions (e.g., GRN-TNFRSF1A and CD14/ADAM9/ADAM17-ITGB1) were maximally enriched within high-CNV tumor-core domains and diminished toward infiltrative margins (Supplementary Figures 5A–D). This evidence concerns the gene TNFRSF1A and neoplasm.