Colorectal cancer is one of the most prevalent forms of cancer worldwide, and a previous study demonstrated that LBP treatment (at concentrations of 250 and 500 μg/mL) reduced the expression of the NLRP3 inflammasome and its associated protein PYCARD while also inhibiting the secretion of inflammatory cytokines (Lian et al., 2023). Here, PYCARD is linked to colorectal cancer.