However, an article in 2020 suggested that Dio3os is elevated in thyroid cancer and, as an oncogenic factor in thyroid cancer, may regulate the expression of Nf-KYB2 through the Dio3o/Lt-7d axis, thereby affecting cell viability, DNA synthesis, infiltration, and migration of thyroid cancer cells [18]. The gene discussed is DIO3OS; the disease is thyroid gland carcinoma.