YAP1 and neoplasm: In summary, existing evidence indicates that SNHG15 promotes epithelial-mesenchymal transition (EMT) and tumor progression in thyroid cancer by regulating the miR-200a-3p/YAP1 axis and the Hippo signaling pathway, while simultaneously influencing the apoptosis process through miR-141 and apoptosis-related proteins (25, 30, 31).