Preclinical evidence from related Vaccinium species suggests VAC's translational potential: V. macrocarpon (cranberry) reduced DMBA‐induced mammary tumors by 73% (tamoxifen 55%); V. myrtillus (bilberry) inhibited 4T1 lung metastasis by 82% in BALB/c mice through suppression of IL‐6/STAT3 signaling. Here, STAT3 is linked to breast cancer.