BDNF and ablepharon macrostomia syndrome: Although CSF NFL and BDNF level measurements yielded comparable sensitivity values at thresholds of 362.7 pg/mL (65.4%) and 156.4 pg/mL (61.5%), respectively, the specificity of CSF BDNF in predicting AMS conversion was far higher (100%) than that of the CSF NFL level (70.4%) (Table 2).