Compared with that in the VBI group, the proportion of MMP-9-positive stained area in the neointima in the VBI group was significantly different (VBI group vs. T2DM+VBI group: 15.07 ± 4.491% vs. 19.68 ± 1.183%, P = 0.0049; Figures 4A, D). This evidence concerns the gene MMP9 and type 2 diabetes mellitus.