Distinguishing FAPhigh and FAPlow expressing tumor cells (Fig. S3A) in TCGA RNA-seq datasets (FAPhigh/low tumor lesions; n = 1292; FAPhigh carcinoma cell lines; n = 237); FAPhigh TC cell lines; n = 6); fibroblastic cell lines (n = 29), the highest increase in both FN1 and FAP expression levels was detected in the FAPhigh TC cell lines mimicking the FAP expression levels of fibroblasts. This evidence concerns the gene FN1 and carcinoma.