The FAP staining correlated to the tumor stage and disease progression with a significant association of FAP expression levels in the Tm and CT compared to the metastatic spread in regional lymph nodes N (p = 0.0225) and perineural invasion Pn (p = 0.017) of anaplastic UTC (Fig. 7E) suggesting an increased tumor cell dissemination to regional lymph nodes and perineuronal vessels with elevated FAP expression. The gene discussed is FAP; the disease is neoplasm.