Western blot analysis further confirmed that TEX19 protein was markedly upregulated in breast cancer cell lines (MCF-7, MDA-MB-231, BT-549) compared with the normal mammary epithelial cell line MCF-10A (Fig. 8B).We selected shTEX19-1, which had a better knockdown effect, for subsequent experiments. The gene discussed is TEX19; the disease is breast carcinoma.