Integration with publicly available single-cell sequencing data revealed that these proteins were mostly macrophage and monocyte-associated with malignant features (TYMP, FCER1G, FCGR1A, SYK, and F13A1), except NNMT, which was highest in cancer-associated fibroblasts (Fig. 5J; Appendix Fig. S3; Table EV4). This evidence concerns the gene SYK and cancer.