The TCGA pan-cancer atlas has identified 12 missense mutations in the CST3 gene across different cancer types according to the cBioPortal platform, including R6H, V57F, F89L, R96Q, C109Y, R119M, K120I, A121E, F122I, A129S, Q133H, and S139L. This evidence concerns the gene CST3 and cancer.