These strains not only effectively improve gut barrier integrity but also inhibit chronic inflammatory responses by regulating pathways such as TLR4/NF‐κB, thus playing an important role in the prevention and treatment of metabolic syndrome (Kang et al. 2022; Liu, Zhao, et al. 2022; Yue et al. 2023). Here, NFKB1 is linked to metabolic syndrome.