The incidence rates for these events were as follows: increased ALT (18.87%), increased AST (13.62%), anemia (32.15%), decreased appetite (10.92%), nausea (16.18%), decreased neutrophil count (23.78%), decreased platelet count (10.16%), rash (5.4%), decreased white blood cell count (26.55%), leukopenia (10.23%), hypothyroidism (8.36%), and hyponatremia (4.19%). This evidence concerns the gene GPT and hypothyroidism.