Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment further implicated platelet activation, dilated and hypertrophic cardiomyopathy, focal adhesion, calcium signaling, extracellular matrix (ECM)-receptor interaction, and protein digestion and absorption as potential pathways involved in the SAA-mediated response (Figure 1D). This evidence concerns the gene SAA2 and hypertrophic cardiomyopathy.