Among 8 studies with CBF, three were used to verify the CCH model only (Jeong et al., 2020; Wang H. et al., 2024; Ji et al., 2025), Buqi Huoxue Tongnao (Gao et al., 2024) Xinshubao tablet (Xiao et al., 2024), and GJ-4 (Pang et al., 2024) could improve CBF in CCH models. This evidence concerns the gene CEBPZ and columnar cell hyperplasia of the breast.