NFE2L2 and eosinophilia-myalgia syndrome: Our previous clinical studies have confirmed that ZSQYJDF can effectively improve the clinical symptoms and inflammatory response of EMs patients, indicating its good therapeutic potential (24–27).This study further revealed through in vivo experiments that ZSQYJDF can significantly inhibit the growth of ectopic lesions in EMs model rats, and its mechanism is closely related to activating the NRF2/HO-1 signaling pathway and enhancing antioxidant defense capacity.