Retrospective analysis of 1999–2018 NHANES data (101,316 participants, 1,500 HF patients) assessed indicators including advanced lung cancer inflammation index (ALI), monocyte-to-albumin ratio (MAR), neutrophil-to-albumin ratio (NAR), red cell distribution width-to-albumin ratio (RAR), prognostic nutritional index (PNI), geriatric nutritional risk index (GNRI), hemoglobin-albumin-lymphocyte-platelet (HALP) score and controlling nutritional status (CONUT) score. This evidence concerns the gene ALB and lung carcinoma.