Based on the postoperative histopathological findings of cavernous hemangioma with granulomatous inflammation in this case, we postulate that cardiac sarcoidosis may have induced microvascular structural alterations, potentially leading to hemangioma formation through VEGF-mediated pathological angiogenesis, given the established association between sarcoidosis and elevated VEGF expression. The gene discussed is VEGFA; the disease is hemangioma.