For example, lncRNA H19, which is abnormally expressed in gastric cancer, influences the infiltration of cancer-associated fibroblasts (CAFs), macrophages, CD4+T cells, and CD8+T cells in the TME through the miR-378a-5p/SERPINH1 axis, thereby promoting the progression of gastric cancer (20). The gene discussed is SERPINH1; the disease is gastric cancer.