ACHE and Alzheimer disease: In addition, the nanocarriers lowered acetylcholinesterase activity (from 1.44 ± 0.25 to 0.96 ± 0.27 U/mg protein) and enhanced antioxidant defences as shown by an increase in catalase activity (from 43.05 ± 4.01 to 58.21 ± 3.99 U/g protein) in the brain of an AD rat model.