As observed for H. pylori infection, lactoferrin’s antimicrobial properties are also gaining interest in the context of inflammatory bowel disease (IBD), a chronic inflammatory and relapsing disorder encompassing conditions such as Crohn’s disease and ulcerative colitis, whose incidence and prevalence is continuously increasing, regardless of sex and socio-economic conditions [2,41,128]. The gene discussed is LTF; the disease is ulcerative colitis.