On univariate analysis, young age (p < 0.005), shorter disease duration (p < 0.005), CD subtype (p = 0.041), zinc deficiency (p < 0.005), high CRP (p < 0.005), high FCP (p < 0.005), low albumin (p < 0.005) and corticosteroids (p < 0.005) were significantly associated with IBD-related hospitalizations but multivariable analysis showed that only zinc deficiency (OR 2.42, 95% CI 1.07–5.48, p = 0.033) and low albumin (OR 9.03. The gene discussed is ALB; the disease is inflammatory bowel disease.