However, despite being significantly older (p = 0.009) and exhibiting significantly higher Ki67 expression levels (p = 0.043), patients with a systemic tumor in CR showed no significant differences in PFS or OS as compared to patients with glioma only, as demonstrated by both Kaplan–Meier analysis and Cox regression (p > 0.05, Figure 5). This evidence concerns the gene MKI67 and central nervous system cancer.