AKT1 and breast neoplasm: Assuming that the morphological changes induced by DADS in SKBR3 are associated with mesenchymal-related changes and based on the knowledge that the Akt pathways in breast tumor cells include the GSK3β/β-catenin axis [33,53], we explored the effects of the garlic derivative on β-catenin, whose overexpression has been shown to increase the activation of HER2 and HER3 receptors, leading to larger tumor sizes [19].