Additionally, the level of soluble forms of PD-1, PD-L1, and PD-L2 in the plasma of patients with EC and the analysis of PD-L1 and PD-L2 gene expression levels in tumor tissue (TT) were assessed in correlation with clinicopathological features of EC patients, and compared to healthy blood donors and the reference group. This evidence concerns the gene CD274 and neoplasm.