The total content of MMP14 in bladder tissue depends on the stage of bladder cancer: it is reported at 10.133 ± 1.414 μg/mg protein for a low grade of the disease and 81.784 ± 9.876 μg/mg protein for a high grade, compared with 7.454 ± 1.183 μg/mg protein for control samples of bladder tissue [55]. This evidence concerns the gene MMP14 and urinary bladder cancer.