PDPN and oculopharyngeal muscular dystrophy: Our systematic review and meta-analysis of the implications of podoplanin in the malignant transformation of OPMDs, carried out across 12 primary-level studies including 857 OPMD patients, demonstrates that podoplanin overexpression is significantly associated with an increased risk of OSCC development in these patients (RR = 3.64, 95% CI = 2.18–6.10, p < 0.001).