Mohamed et al. (2018) observed that HPV-positive OPSCC (oropharyngeal squamous cell carcinoma) tumors were associated with increased AR expression as compared to HPV-negative tumors [155], and oropharyngeal tumors were more likely to express sex hormone receptors, including AR and ERa, as compared to other sites in HNSCC [155,156]. This evidence concerns the gene AR and head and neck squamous cell carcinoma.