The PD-L1 × CD3 TCE exhibited potent tumor killing (EC50 = 0.00336 nM) in RKO-PBMC cocultures (Figure 5C), while the CD318-MMAE ADC showed nanomolar growth inhibition (IC50 = 48.87 nM) against RKO monolayers (Figure 5D). This evidence concerns the gene CD274 and neoplasm.