The association of CXCL1 increase to the inflammatory activation of rat vascular SMC induced by hypertension [33], to the causes of hypertension and MMP9 release in human diseases [32,34], and to AAA growth [35] support the potential relevance of Lad effects over CXCL1 in the perspective of AAA therapy. This evidence concerns the gene CXCL1 and triple-A syndrome.