To this end, the expression of MYC, MITF, CCND1 (encoding cyclin D1), and CDKN1A (encoding p21), along with BIRC5 and CTNNB1 (encoding β-catenin), was merged with clinical data regarding survival time of melanoma patients from the TCGA SKCM dataset [46] using the TCGA biolinks workflow in R. The survival and survminer packages were then used to fit the multivariate Cox regression model (Figure 7C). This evidence concerns the gene CDKN1A and melanoma.