CTNNB1 and melanoma: To this end, the expression of MYC, MITF, CCND1 (encoding cyclin D1), and CDKN1A (encoding p21), along with BIRC5 and CTNNB1 (encoding β-catenin), was merged with clinical data regarding survival time of melanoma patients from the TCGA SKCM dataset [46] using the TCGA biolinks workflow in R. The survival and survminer packages were then used to fit the multivariate Cox regression model (Figure 7C).