Among 2164 subjects (836 ischemic heart disease patients and 1328 controls), carriers of the C allele at the rs1058074 locus of SERBP1 have a significantly reduced risk of disease (OR = 0.63, 95% CI: 0.43–0.93, p = 0.02), and this allele is associated with a decrease in serum low-density lipoprotein cholesterol (LDL-C) levels [37]. Here, SERBP1 is linked to coronary artery disorder.