Clinical sample analysis shows that the median survival time of liver cancer patients with high SERBP1 expression (n = 86) is 14.6 months, which is significantly shorter than that of patients with low SERBP1 expression (32.8 months), and the expression level of SERBP1 is positively correlated with tumor microvessel density (MVD) [8]. This evidence concerns the gene SERBP1 and liver cancer.