NKm cells can be found in the tumor microenvironment; they secrete high levels of IFNγ, Perforin (PRF), Granulysine (GNLY), and Granzyme A and B (GZMA, GZMB) upon re-stimulation [9], and their impaired function is associated with cancer growth and dissemination [10]. This evidence concerns the gene GNLY and neoplasm.