With this, we were able to conclude that proteins found to be of higher abundance in DMD cell lines could be mainly annotated to the extracellular region (nine proteins, GO Term enrichment analysis: p-value 2.8 × 10−4), including Emilin-1, Collagen Type VI Alpha 2, Apolipoprotein E, Collagen Type XVIII Alpha 1 Chain, Annexin A6, Serpin H1, Nidogen 2, Collagen Type VI Alpha 3 Chain and Annexin A2, and to the sarcolemma (four proteins, GO Term enrichment analysis: p-value 2.8 × 10−4), including Collagen Type VI Alpha 2 Chain and 3 Chain, and Annexins A6 and A2 (Figure 2a). This evidence concerns the gene ANXA2 and Duchenne muscular dystrophy.