XBP1 and COVID-19: By 6 weeks post-inclusion (T2), COVID-19 hypermethylation of genes with lowest p-value included NXN, FMNL2, ZBTB46, SLC35F3, and SHQ1, and the hypomethylated genes included ELMO1, XBP1, GRIK1, TNFAIP8, and SH3BP5 (Figure 4C).