In addition to the anatomical variations in bone structure observed in pediatric patients, such as a flatter glenoid fossa, various other conditions may predispose to TMJ dislocation, including connective tissue disorders like Ehlers-Danlos Syndrome, which are associated with structural defects in collagen and elastin leads to loss of stability and ligament support [45,46]. This evidence concerns the gene ELN and Ehlers-Danlos syndrome.