FGF23 and hypophosphatemia: According to a systemic review of 769 articles, hypophosphatemia (99.8%), increased FGF23 (95.5%), increased ALP (94.9%), and decreased 1,25(OH)2D (69.8) were observed at TIO diagnosis, and serum Pi and FGF23 levels were normalized in approximately 91.5% and 81.4% of patients, respectively [21].