However, in the multivariable model, only three factors remained independent predictors of mortality: T4 tumor stage (HR 1.47, 95% C.I.: 1.08–2.01, p = 0.015), anemia defined as Hb < 11.85 g/dL (HR 1.70, 95% C.I.: 1.27–2.27, p < 0.001), and leukocytosis defined as WBC > 11.71 × 109/L (HR 1.54, 95% C.I.: 1.15–2.05, p = 0.004). The gene discussed is GSTM1; the disease is anemia (phenotype).